特異性

The mouse monoclonal antibody MEM-G/9 reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its β2-microglobulin associated form. Reactivity with HLA-G3 was also reported. The antibody MEM-G/9 is standard reagent thoroughly validated during 3rd International Conference on HLA-G (Paris, 2003).

抗原情報

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Fournel S, Huc X, Aguerre-Girr M, Solier C, Legros M, Praud-Brethenou C, Moussa M, Chaouat G, Berrebi A, Bensussan A, Lenfant F, Le Bouteiller P: Comparative reactivity of different HLA‑G monoclonal antibodies to soluble HLA‑G molecules. Tissue·Antigens. 2000·Jun; 55(6):510‑8. <·PMID:·10902607·>
• Fuzzi B, Rizzo R, Criscuoli L, Noci I, Melchiorri L, Scarselli B, Bencini E, Menicucci A, Baricordi OR: HLA‑G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy. Eur·J·Immunol. 2002·Feb; 32(2):311‑5. <·PMID:·11807769·>
• Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsí V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor‑1 distinguishes between conformed and beta 2‑microglobulin‑free HLA‑G molecules. J·Immunol. 2005·Oct·15; 175(8):4866‑74. <·PMID:·16210588·>
• Lopez AS, Alegre E, LeMaoult J, Carosella E, Gonzalez A: Regulatory role of tryptophan degradation pathway in HLA‑G expression by human monocyte‑derived dendritic cells. Mol·Immunol. 2006·Jul; 43(14):2151‑60. <·PMID:·16490253·>
• Lozano JM, Gonzalez R, Kindelan JM, Rouas-Freiss N, Caballos R, Dausset J, Carosella ED, Pena J: Monocytes and T lymphocytes in HIV‑1‑positive patients express HLA‑G molecule. AIDS. 2002·Feb·15; 16(3):347‑51. <·PMID:·11834945·>
• Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA‑G or HLA‑E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum·Immunol. 2003·Mar; 64(3):315‑26. <·PMID:·12590976·>
• Pangault C, Le Friec G, Caulet-Maugendre S, Lena H, Amiot L, Guilloux V, Onno M, Fauchet R: Lung macrophages and dendritic cells express HLA‑G molecules in pulmonarydiseases. Hum·Immunol. 2002·Feb; 63(2):83‑90. <·PMID:·11821155·>
• Zhao L, Teklemariam T, Hantash BM: Reassessment of HLA‑G isoform specificity of MEM‑G/9 and 4H84 monoclonal antibodies. Tissue·Antigens. 2012·Sep; 80(3):231‑8. <·PMID:·22738368·>
• Abstracts from the 3rd International Conference on HLA‑G; Paris, July 2003. Tissue·Antigens. 2003; 62(4):340‑57. <·Wiley·j.1399-0039·>