CyFlow CD116 Purified
品番 | BW148413 | ||
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抗体名 | Anti-Hu CD116 PURI,4H1 | ||
包装単位 | 0.1 mg | ||
濃度 | 1 mg/ml | ||
容量 | 0.1 ml | ||
関連製品 (アイソタイプコントロール) |
Mouse IgG1 Purified (BJ561896) Mouse IgG1 Purified (AS224818) |
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反応性|交差吸着 | Human | レーザー | |
抗原 | CD116, GMCSFR alpha | 最大蛍光波長 | - |
クローン | 4H1 | 最大励起波長 | - |
ホスト | Mouse | 標識/Format | Purified |
アイソタイプ | IgG1 | 研究分野 | Immunophenotyping |
クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu CD116 PURI,4H1
特異性
The mouse monoclonal antibody 4H1 recognizes CD116 antigen, a 80 kDa GM-CSF receptor α subunit expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
抗原情報
CD116 (GM-CSF R α) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common β chain subunit shared with IL-3 and IL-5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.
利用方法
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP: IL‑15 trans‑presentation promotes human NK cell development and differentiation in vivo. J·Exp·Med. 2009·Jan·16; 206(1):25‑34. <·PMID:·19103877·>
• Koba C, Haruta M, Matsunaga Y, Matsumura K, Haga E, Sasaki Y, Ikeda T, Takamatsu K, Nishimura Y, Senju S: Therapeutic effect of human iPS‑cell‑derived myeloid cells expressing IFN‑β: against peritoneally disseminated cancer in xenograft models. PLoS·One. 2013·Jun·24; 8(6):e67567. <·PMID:·23826321·>
• Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J: Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS·One. 2013·Apr·26; 8(4):e62761. <·PMID:·23658649·>
• Stomski FC, Woodcock JM, Zacharakis B, Bagley CJ, Sun Q, Lopez AF: Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte‑macrophage colony‑stimulating factor, and interleukin 5 receptors essential for disulfide‑linked receptor heterodimerization and activation of all three receptors. J·Biol·Chem. 1998·Jan·9; 273(2):1192‑9. <·PMID:·9422786·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN