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CyFlow CD116 Purified

品番 BW148413
抗体名 Anti-Hu CD116 PURI,4H1
包装単位 0.1 mg
濃度 1 mg/ml
容量 0.1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 Purified (BJ561896)
Mouse IgG1 Purified (AS224818)
反応性|交差吸着 Human レーザー
抗原 CD116, GMCSFR alpha 最大蛍光波長 -
クローン 4H1 最大励起波長 -
ホスト Mouse 標識/Format Purified
アイソタイプ IgG1 研究分野 Immunophenotyping
クローナリティ monoclonal 用途

Flow cytometry
Immunoprecipitation
Western blot
Immunohistochemistry (frozen sections)

Anti-Hu CD116 PURI,4H1

特異性

The mouse monoclonal antibody 4H1 recognizes CD116 antigen, a 80 kDa GM-CSF receptor α subunit expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.

抗原情報

CD116 (GM-CSF R α) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common β chain subunit shared with IL-3 and IL-5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP: IL‑15 trans‑presentation promotes human NK cell development and differentiation in vivo. J·Exp·Med. 2009·Jan·16; 206(1):25‑34. <·PMID:·19103877·>
• Koba C, Haruta M, Matsunaga Y, Matsumura K, Haga E, Sasaki Y, Ikeda T, Takamatsu K, Nishimura Y, Senju S: Therapeutic effect of human iPS‑cell‑derived myeloid cells expressing IFN‑β: against peritoneally disseminated cancer in xenograft models. PLoS·One. 2013·Jun·24; 8(6):e67567. <·PMID:·23826321·>
• Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J: Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS·One. 2013·Apr·26; 8(4):e62761. <·PMID:·23658649·>
• Stomski FC, Woodcock JM, Zacharakis B, Bagley CJ, Sun Q, Lopez AF: Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte‑macrophage colony‑stimulating factor, and interleukin 5 receptors essential for disulfide‑linked receptor heterodimerization and activation of all three receptors. J·Biol·Chem. 1998·Jan·9; 273(2):1192‑9. <·PMID:·9422786·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD116 Purified (4H1) BW148413 TDS (US)