CyFlow CD271 PE-Cy7
品番 | CR413544 | ||
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抗体名 | Anti-Hu CD271 PE-CY7,NGFR5 | ||
包装単位 | 100 tests | ||
濃度 | - | ||
容量 | 0.4 ml | ||
関連製品 (アイソタイプコントロール) |
Mouse IgG1 PE-Cy7 (CF148611) |
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反応性|交差吸着 | Human | Non-Human Primates | Cat | Ferret | Rabbit | レーザー | Blue, Green, Yellow |
抗原 | CD271, LNGFR, p75NTR | 最大蛍光波長 | 785 nm |
クローン | NGFR5 | 最大励起波長 | 496 nm, 565 nm |
ホスト | Mouse | 標識/Format | PE-Cy7 |
アイソタイプ | IgG1 | 研究分野 | Immunophenotyping | Neurobiology |
クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu CD271 PE-CY7,NGFR5
特異性
The mouse monoclonal antibody NGFR5 (originally C34C) recognizes CD271 antigen, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
抗原情報
CD271 (NGFR, p75NGFR, p75NTR) is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
利用方法
The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Alpers CE, Hudkins KL, Ferguson M, Johnson RJ, Schatteman GC, Bothwell M: Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys. Lab·Invest. 1993·Dec; 69(6):703‑13. <·PMID:·7903404·>
• Marano N, Dietzschold B, Earley JJ Jr, Schatteman G, Thompson S, Grob P, Ross AH, Bothwell M, Atkinson BF, Koprowski H: Purification and amino terminal sequencing of human melanoma nerve growth factor receptor. J·Neurochem. 1987·Jan; 48(1):225‑32. <·PMID:·3025363·>
• Schatteman GC, Gibbs L, Lanahan AA, Claude P, Bothwell M: Expression of NGF receptor in the developing and adult primate central nervous system. J·Neurosci. 1988·Mar; 8(3):860‑73. <·PMID:·2831315·>
• Thompson SJ, Schatteman GC, Gown AM, Bothwell M: A monoclonal antibody against nerve growth factor receptor: Immunohistochemical analysis of normal and neoplastic human tissue. Am·J·Clin·Pathol. 1989·Oct; 92(4):415‑23. <·PMID:·2552791·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN