CyFlow CD61 Purified
品番 | BH224849 | ||
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抗体名 | Anti-Hu CD61 PURI,VIPL2 | ||
包装単位 | 0.1 mg | ||
濃度 | 1 mg/ml | ||
容量 | 0.1 ml | ||
関連製品 (アイソタイプコントロール) |
Mouse IgG1 Purified (BJ561896) Mouse IgG1 Purified (AS224818) |
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反応性|交差吸着 | Human | Non-Human Primates | レーザー | |
抗原 | CD61, GPIIIa | 最大蛍光波長 | - |
クローン | VIPL2 | 最大励起波長 | - |
ホスト | Mouse | 標識/Format | Purified |
アイソタイプ | IgG1 | 研究分野 | Immunophenotyping |
クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu CD61 PURI,VIPL2
特異性
The mouse monoclonal antibody VIPL2 recognizes CD61 antigen, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leukocytes and smooth muscle cells.
抗原情報
CD61 (β3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.
利用方法
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Barrett L, Dai C, Gamberg J, Gallant M, Grant M: Circulating CD14‑CD36+ peripheral blood mononuclear cells constitutively produce interleukin‑10. J·Leukoc·Biol. 2007·Jul; 82(1):152‑60. <·PMID:·17412916·>
• Ciarlet M, Crawford SE, Cheng E, Blutt SE, Rice DA, Bergelson JM, Estes MK: VLA‑2 (alpha2beta{01} integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J·Virol. 2002·Feb; 76(3):1109‑23. <·PMID:·11773387·>
• Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, Buck DW, Schmitz J: BDCA‑2, BDCA‑3, and BDCA‑4: three markers for distinct subsets of dendritic cells in human peripheral blood. J·Immunol. 2000·Dec·1; 165(11):6037‑46. <·PMID:·11086035·>
• Mondal D, Williams CA, Ali M, Eilers M, Agrawal KC: The HIV‑1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells. Exp·Biol·Med·(Maywood). 2005·Oct; 230(9):631‑44. <·PMID:·16179731·>
• Roberts MS, Woods AJ, Dale TC, Van Der Sluijs P, Norman JC: Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins. Mol·Cell·Biol. 2004·Feb; 24(4):1505‑15. <·PMID:·14749368·>
• Williams CA, Mondal D, Agrawal KC: The HIV‑1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP. Exp·Biol·Med·(Maywood). 2005·Dec; 230(11):872‑84. <·PMID:·16339753·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN