CyFlow IgG (Fab) PE-Cy7
| 品番 | AC312387 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu IGG (FAB) PE-CY7,4A11 | ||
| 包装単位 | 100 tests | ||
| 濃度 | - | ||
| 容量 | 0.4 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Human | レーザー | Blue, Green, Yellow |
| 抗原 | IgG (Fab) | 最大蛍光波長 | 785 nm |
| クローン | 4A11 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Mouse | 標識/Format | PE-Cy7 |
| アイソタイプ | IgG2b | 研究分野 | Immunoglobulins |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu IGG (FAB) PE-CY7,4A11
特異性
The mouse monoclonal antibody 4A11 recognizes Fab fragment of human immunoglobulin G (IgG).
抗原情報
Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75% of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.
利用方法
The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann·Rheum·Dis. 1980·Apr; 39(2):129‑34. <·PMID:·6966908·>
• Brinkmann V, Heusser CH: T cell‑dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell·Immunol. 1993·Dec; 152(2):323‑32. <·PMID:·8258141·>
• Franklin EC: Structure and function of immunoglobulins. Acta·Endocrinol·Suppl·(Copenh). 1975; 194:77‑95. <·PMID:·47690·>
• Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin·Chem. 1975·May; 21(6):667‑71. <·PMID:·1122610·>
• Fujii Y, Kaneko S, Nzou SM, Mwau M, Njenga SM, Tanigawa C, Kimotho J, Mwangi AW, Kiche I, Matsumoto S, Niki M, Osada-Oka M, Ichinose Y, Inoue M, Itoh M, Tachibana H, Ishii K, Tsuboi T, Yoshida LM, Mondal D, Haque R, Hamano S, Changoma M, Hoshi T, Kamo K, Karama M, Miura M, Hirayama K: Serological Surveillance Development for Tropical Infectious Diseases Using Simultaneous Microsphere-Based Multiplex Assays and Finite Mixture Models. PLoS·Negl·Trop·Dis. 2014·Jul·31; 8(7):e3040. <·PMID:·25078404·>
• Wang H, Lee HK, Bukowski JF, Li H, Mariuzza RA, Chen ZW, Nam KH, Morita CT: Conservation of nonpeptide antigen recognition by rhesus monkey V gamma 2V delta 2 T cells.. J·Immunol. 2003·Apr·1; 170(7):3696-706. <·PMID:·12646635·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN