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CyFlow CD68 Purified

品番 CY184980
抗体名 Anti-Hu CD68 PURI,Y1/82A
包装単位 0.1 mg
濃度 1 mg/ml
容量 0.1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG2b Purified (AS131472)
Mouse IgG2b Purified (CK823368)
反応性|交差吸着 Human レーザー
抗原 CD68, Macrosialin, gp110 最大蛍光波長 -
クローン Y1/82A 最大励起波長 -
ホスト Mouse 標識/Format Purified
アイソタイプ IgG2b 研究分野 Immunophenotyping
クローナリティ monoclonal 用途

Flow cytometry
Immunohistochemistry (frozen sections)

Anti-Hu CD68 PURI,Y1/82A

特異性

The mouse monoclonal antibody Y1/82A recognizes CD68 antigen, a 110 kDa glycoprotein expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells.

抗原情報

CD68 (LAMP4, SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Doussis IA, Gatter KC, Mason DY: CD68 reactivity of non‑macrophage derived tumours in cytological specimens. J·Clin·Pathol. 1993·Apr; 46(4):334‑6. <·PMID:·7684403·>
• Doussis IA, Gatter KC, Mason DY: CD68 reactivity of non‑macrophage derived tumours in cytological specimens. J·Clin·Pathol. 1993·Apr; 46(4):334‑6. <·PMID:·7684403·>
• Holness CL, Simmons DL: Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. Blood. 1993·Mar·15; 81(6):1607‑13. <·PMID:·7680921·>
• Mack CL, Tucker RM, Sokol RJ, Karrer FM, Kotzin BL, Whitington PF, Miller SD: Biliary atresia is associated with CD4+ Th1 cell‑mediated portal tract inflammation. Pediatr·Res. 2004·Jul; 56(1):79‑87. <·PMID:·15128911·>
• Ulanova M, Tarkowski A, Hahn-Zoric M, Hanson LA: The Common vaccine adjuvant aluminum hydroxide up‑regulates accessory properties of human monocytes via an interleukin‑4‑dependent mechanism. Infect·Immun. 2001·Feb; 69(2):1151‑9. <·PMID:·11160013·>
• Yamagami S, Yokoo S, Amano S, Ebihara N: Characterization of bone marrow derived cells in the substantia propria of the human conjunctiva. Invest·Ophthalmol·Vis·Sci. 2007·Oct; 48(10):4476‑81. <·PMID:·17898268·>