CyFlow HLA-E Purified
品番 | CT617431 | ||
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抗体名 | Anti-Hu HLA-E PURI,MEM-E/08 | ||
包装単位 | 0.1 mg | ||
濃度 | 1 mg/ml | ||
容量 | 0.1 ml | ||
関連製品 (アイソタイプコントロール) |
Mouse IgG1 Purified (BJ561896) Mouse IgG1 Purified (AS224818) |
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反応性|交差吸着 | Human | レーザー | |
抗原 | HLA-E | 最大蛍光波長 | - |
クローン | MEM-E/08 | 最大励起波長 | - |
ホスト | Mouse | 標識/Format | Purified |
アイソタイプ | IgG1 | 研究分野 | MHC |
クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu HLA-E PURI,MEM-E/08
特異性
The mouse monoclonal antibody MEM-E/08 recognizes native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.
抗原情報
利用方法
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsí V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor‑1 distinguishes between conformed and beta 2‑microglobulin‑free HLA‑G molecules. J·Immunol. 2005·Oct·15; 175(8):4866‑74. <·PMID:·16210588·>
• Lo Monaco E, Tremante E, Cerboni C, Melucci E, Sibilio L, Zingoni A, Nicotra MR, Natali PG, Giacomini P: Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. Neoplasia. 2011·Sep; 13(9):822‑30. <·PMID:·21969815·>
• Nachmani D, Zimmermann A, Oiknine Djian E, Weisblum Y, Livneh Y, Khanh Le VT, Galun E, Horejsi V, Isakov O, Shomron N, Wolf DG, Hengel H, Mandelboim O: MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS·Pathog. 2014·Feb·27; 10(2):e1003963. <·PMID:·24586166·>
• Palmisano GL, Contardi E, Morabito A, Gargaglione V, Ferrara GB, Pistillo MP: HLA‑E surface expression is independent of the availability of HLA class I signal sequence‑derived peptides in human tumor cell lines. Hum·Immunol. 2005·Jan; 66(1):42705. <·PMID:·15620456·>
• Sibilio L, et al.: Abstract 45 from the 3rd International Conference on HLA‑G; Paris, July 2003. Tissue·Antigens. 2003; 62:339. <·No·PMID·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN