CyFlow CD90.2 PE
| 品番 | CN347786 | ||
|---|---|---|---|
| 抗体名 | Anti-Ms CD90.2 PE,1aG4/C5 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 0.1 mg/ml | ||
| 容量 | 1 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Mouse | レーザー | Blue, Green, Yellow |
| 抗原 | CD90.2 | 最大蛍光波長 | 576 nm |
| クローン | 1aG4/C5 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Mouse | 標識/Format | PE |
| アイソタイプ | IgG3 | 研究分野 | Immunophenotyping | MHC |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Ms CD90.2 PE,1aG4/C5
特異性
The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse CD90 (Thy-1); it does not cross-react with Thy-1.1 alloantigen. CD90 is a 18-35 kDa cell surface GPI linked glycoprotein (immunoglobulin superfamily); in mouse it is abundant on thymocytes and peripheral T lymphocytes.
抗原情報
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. In the mouse, CD90 is expressed mainly on thymocytes and peripheral T lymphocytes. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
利用方法
The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Bradley JE, Ramirez G, Hagood JS: Roles and regulation of Thy‑1, a context‑dependent modulator of cell phenotype. Biofactors. 2009·May-Jun; 35(3):258‑65. <·PMID:·19422052·>
• Draber P, Zikan J, Vogtiskova M: Establishment and characterization of permanent murine hybridomas secreting monoclonal anti‑thy‑1 antibodies. J·Immunogenet. 1980·Dec; 7(6):455‑74. <·PMID:·6787139·>
• Draberova L, Draber P: Thy‑1 glycoprotein and src‑like protein‑tyrosine kinase p53/p56lyn are associated in large detergent‑resistant complexes in rat basophilic leukemiacells. Proc·Natl·Acad·Sci·USA. 1993·Apr·15; 90(8):3611‑5. <·PMID:·7682713·>
• Haeryfar SM, Hoskin DW: Thy‑1: more than a mouse pan‑T cell marker. J·Immunol. 2004·Sep·15; 173(6):3581‑8. <·PMID:·15356100·>
• Heneberg P, Lebduska P, Draberova L, Korb J, Draber P: Topography of plasma membrane microdomains and its consequences for mast cell signaling. Eur·J·Immunol. 2006·Oct; 36(10):2795‑806. <·PMID:·17013982·>
• Rege TA, Hagood JS: Thy‑1 as a regulator of cell‑cell and cell‑matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB·J. 2006·Jun; 20(8):1045‑54. <·PMID:·16770003·>
• Rege TA, Hagood JS: Thy‑1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses. Biochim·Biophys·Acta. 2006·Oct; 1763(10):991‑9. <·PMID:·16996153·>
• Zikan J, Draber P, Vojtiskova M: Monoclonal IgG3 (kappa) antibodies against murine Thy‑1.2 antigen produced by murine hybridomas: Differences in the specificity of the antigen binding site and in the structure of the hinge region. Folia·Biol·(Praha). 1982; 28(6):377‑94. <·PMID:·6186535·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN