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CyFlow CD61 PE-Cy7

品番 CG662113
抗体名 Anti-Hu CD61 PE-CY7,VIPL2
包装単位 100 tests
濃度 -
容量 0.4 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 PE-Cy7 (CF148611)
反応性|交差吸着 Human | Non-Human Primates レーザー Blue, Green, Yellow
抗原 CD61, GPIIIa 最大蛍光波長 785 nm
クローン VIPL2 最大励起波長 496 nm, 565 nm
ホスト Mouse 標識/Format PE-Cy7
アイソタイプ IgG1 研究分野 Immunophenotyping
クローナリティ monoclonal 用途

Flow cytometry

Anti-Hu CD61 PE-CY7,VIPL2

特異性

The mouse monoclonal antibody VIPL2 recognizes CD61 antigen, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leukocytes and smooth muscle cells.

抗原情報

CD61 (β3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.

利用方法

The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Barrett L, Dai C, Gamberg J, Gallant M, Grant M: Circulating CD14‑CD36+ peripheral blood mononuclear cells constitutively produce interleukin‑10. J·Leukoc·Biol. 2007·Jul; 82(1):152‑60. <·PMID:·17412916·>
• Ciarlet M, Crawford SE, Cheng E, Blutt SE, Rice DA, Bergelson JM, Estes MK: VLA‑2 (alpha2beta{01} integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J·Virol. 2002·Feb; 76(3):1109‑23. <·PMID:·11773387·>
• Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, Buck DW, Schmitz J: BDCA‑2, BDCA‑3, and BDCA‑4: three markers for distinct subsets of dendritic cells in human peripheral blood. J·Immunol. 2000·Dec·1; 165(11):6037‑46. <·PMID:·11086035·>
• Mondal D, Williams CA, Ali M, Eilers M, Agrawal KC: The HIV‑1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells. Exp·Biol·Med·(Maywood). 2005·Oct; 230(9):631‑44. <·PMID:·16179731·>
• Roberts MS, Woods AJ, Dale TC, Van Der Sluijs P, Norman JC: Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins. Mol·Cell·Biol. 2004·Feb; 24(4):1505‑15. <·PMID:·14749368·>
• Williams CA, Mondal D, Agrawal KC: The HIV‑1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP. Exp·Biol·Med·(Maywood). 2005·Dec; 230(11):872‑84. <·PMID:·16339753·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD61 PE-Cy7 (VIPL2) CG662113 TDS (US)