CyFlow Kappa-LC Biotin
品番 | CA388668 | ||
---|---|---|---|
抗体名 | Anti-Hu KAPPA-LC BIOTIN,TB28-2 | ||
包装単位 | 0.1 mg | ||
濃度 | 1 mg/ml | ||
容量 | 0.1 ml | ||
関連製品 (アイソタイプコントロール) |
- | ||
反応性|交差吸着 | Human | レーザー | |
抗原 | κ light chains | 最大蛍光波長 | - |
クローン | TB28-2 | 最大励起波長 | - |
ホスト | Mouse | 標識/Format | Biotin |
アイソタイプ | IgG1 | 研究分野 | Immunoglobulins |
クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu KAPPA-LC BIOTIN,TB28-2
特異性
The mouse monoclonal antibody TB28-2 recognizes human Ig κ light chains of both secreted and cell surface immunoglobulin. It detects also free κ light chains.
抗原情報
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (κ and λ; both having a molecular weight of 22.5kDa). κ and λ consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of κ to λ is 70:30.
利用方法
The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Böttcher S, Ritgen M, Buske S, Gesk S, Klapper W, Hoster E, Hiddemann W, Unterhalt M, Dreyling M, Siebert R, Kneba M, Pott C: EU MCL MRD Group: Minimal residual disease detection in mantle cell lymphoma: methods and significance of four‑color flow cytometry compared to consensus IGH‑polymerase chain reaction at initial staging and for follow‑up examinations. Haematologica. 2008·Apr; 93(4):551‑9. <·PMID:·18379010·>
• Jourdan M, Caraux A, De Vos J, Fiol G, Larroque M, Cognot C, Bret C, Duperray C, Hose D, Klein B: An in vitro model of differentiation of memory B cells into plasmablasts andplasma cells including detailed phenotypic and molecular characterization. Blood. 2009·Dec·10; 114(25):5173‑81. <·PMID:·19846886·>
• Karandikar NJ, Aquino DB, McKenna RW, Kroft SH: Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome: An immunophenotypic analysis. Am·J·Clin·Pathol. 2001·Aug; 116(2):204‑10. <·PMID:·11488066·>
• Kiyotaki M, Cooper MD, Bertoli LF, Kearney JF, Kubagawa H: Monoclonal anti‑Id antibodies react with varying proportions of human B lineage cells. J·Immunol. 1987·Jun·15; 138(12):4150‑8. <·PMID:·3495581·>
• Nakamura T, Kubagawa H, Cooper MD: Heterogeneity of immunoglobulin‑associated molecules on human B cells identified by monoclonal antibodies. Proc·Natl·Acad·Sci·USA. 1992·Sep·15; 89(18):8522‑6. <·PMID:·1382292·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN