CyFlow CD300e PE
| 品番 | BZ437583 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu CD300e PE,UP-H2 | ||
| 包装単位 | 100 tests | ||
| 濃度 | - | ||
| 容量 | 1 ml | ||
| 関連製品 (アイソタイプコントロール) |
Mouse IgG1 PE (BV655324) |
||
| 反応性|交差吸着 | Human | レーザー | Blue, Green, Yellow |
| 抗原 | CD300e, IREM-2, LMIR6 | 最大蛍光波長 | 576 nm |
| クローン | UP-H2 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Mouse | 標識/Format | PE |
| アイソタイプ | IgG1 | 研究分野 | Immunophenotyping |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu CD300e PE,UP-H2
特異性
The mouse monoclonal antibody UP-H2 recognizes CD300e antigen, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
抗原情報
CD300e (IREM-2; immune receptor expressed by myeloid cells 2, CLM2 or LMIR6) is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
利用方法
The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Aguilar H, Alvarez-Errico D, García-Montero AC, Orfao A, Sayós J, López-Botet M: Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J·Immunol. 2004·Dec·1; 173(11):6703‑11. <·PMID:·15557162·>
• Brckalo T, Calzetti F, Pérez-Cabezas B, Borrás FE, Cassatella MA, López-Botet M: Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. Eur·J·Immunol. 2010·Mar; 40(3):722‑32. <·PMID:·20039296·>
• Clark GJ, Ju X, Tate C, Hart DN: The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions. Trends·Immunol. 2009·May; 30(5):209‑17. <·PMID:·19359216·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN