CyFlow HLA-Class I PE
| 品番 | BX007187 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu HLA-ClAss I PE,MEM-123 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 0.1 mg/ml | ||
| 容量 | 1 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Human | Non-Human Primates | Cow | レーザー | Blue, Green, Yellow |
| 抗原 | HLA-Class I | 最大蛍光波長 | 576 nm |
| クローン | MEM-123 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Mouse | 標識/Format | PE |
| アイソタイプ | IgG3 | 研究分野 | MHC |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu HLA-ClAss I PE,MEM-123
特異性
The mouse monoclonal antibody MEM-123 recognizes all human classical MHC Class I molecules in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-block the antibody MEM-G/9.
抗原情報
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant β2-microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
利用方法
The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• van den Berg CW, Gonçalves-de-Andrade RM, Magnoli FC, Tambourgi DV: Loxosceles spider venom induces the release of thrombomodulin and endothelial protein C receptor: implications for the pathogenesis of intravascular coagulation as observed in loxoscelism.. J·Thromb·Haemost. 2007·May; 5(5):989-95. <·PMID:·17229042·>
• Bonomi A, Coccè V, Cavicchini L, Sisto F, Dossena M, Balzarini P, Portolani N, Ciusani E, Parati E, Alessandri G, Pessina A: Adipose tissue-derived stromal cells primed in vitro with paclitaxel acquire anti-tumor activity. Int·J·Immunopathol·Pharmacol. 2013·Jan-Mar; 26(1·Suppl):33-41. <·PMID:·24046947·>
• Van Den Berg CW, De Andrade RM, Magnoli FC, Marchbank KJ, Tambourgi DV: Loxosceles spider venom induces metalloproteinase mediated cleavage of MCP/CD and MHCI and induces protection against C‐mediated lysis. Immunology. 2002·Sep; 107(1):102-10. <·PMID:·12225368·>
• Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan-Ngum W, Chomanee N, Charngkaew K, Tangthawornchaikul N, Limpitikul W, Vasanawathana S, Malasit P, Avirutnan P: Microparticles provide a novel biomarker to predict severe clinical outcomes of dengue virus infection.. J·Virol. 2015·Feb; 89(3):1587-607. <·PMID:·25410854·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN