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CyFlow CK-Pan Alexa Fluor 488

品番 BW538693
抗体名 CK-PAn AF 488,C-11
包装単位 0.1 mg
濃度 0.1 mg/ml
容量 1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 Alexa Fluor™ 488 (AD892927)
反応性|交差吸着 Mammalian レーザー Blue
抗原 Cytokeratin (Pan-reactive) 最大蛍光波長 519 nm
クローン C-11 最大励起波長 495 nm
ホスト Mouse 標識/Format Alexa Fluor™ 488
アイソタイプ IgG1 研究分野 Cytoskeleton
クローナリティ monoclonal 用途

Flow cytometry

CK-PAn AF 488,C-11

特異性

The mouse monoclonal antibody C-11 recognizes Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

抗原情報

Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

利用方法

The reagent is designed for Flow Cytometry analysis. Suggested working usage is 10 µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator.

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Bartek J, Vojtesek B, Staskova Z, Bartkova J, Kerekes Z, Rejthar A, Kovarik J: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J·Pathol. 1991·Jul; 164(3):215‑24. <·PMID:·1716305·>
• Broekema M, Harmsen MC, Koerts JA, Petersen AH, van Luyn MJ, Navis G, Popa ER: Determinants of tubular bone marrow‑derived cell engraftment after renal ischemia/reperfusion in rats. Kidney·Int. 2005·Dec; 68(6):2572‑81. <·PMID:·16316332·>
• Hamakawa H, Sumida T, Tanioka H, Sogawa K, Yamada T: Extraction of cytokeratin from the human submandibular gland and its electrophoretic analysis. Res·Commun·Mol·Pathol·Pharmacol. 1998·Aug; 101(2):115‑26. <·PMID:·9821208·>
• Kovarik J, Rejthar A, Lauerova L, Vojtesek B, Bartkova J: Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread. Int·J·Cancer·Suppl. 1988; 3:50‑5. <·PMID:·2463228·>
• Vojtĕsek B, Stasková Z, Nenutil R, Lauerová L, Kovarík J, Rejthar A, Bártková J, Bártek J: Monoclonal antibodies recognizing different epitopes of cytokeratin No.18. Folia·Biol·(Praha). 1989; 35(6):373‑82. <·PMID:·2483834·>