CyFlow CD41 PE
| 品番 | BQ684614 | ||
|---|---|---|---|
| 抗体名 | Anti-Ms CD41 PE,MWReg30 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 0.5 mg/ml | ||
| 容量 | 0.2 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Mouse | レーザー | Blue, Green, Yellow |
| 抗原 | CD41, gpIIb | 最大蛍光波長 | 576 nm |
| クローン | MWReg30 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Rat | 標識/Format | PE |
| アイソタイプ | IgG1 | 研究分野 | Immunophenotyping | MHC |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Ms CD41 PE,MWReg30
特異性
The rat monoclonal antibody MWReg30 recognizes mouse CD41 antigen, a transmembrane glycoprotein (integrin family) composed of two chains GPIIb α (heavy chain; 120 kDa) and GPIIb β (light chain; 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
抗原情報
CD41 (GPIIb; platelet glycoprotein IIb) is composed of two subunits (120 kDa GPIIb α and 23 kDa GPIIb β) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
利用方法
The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C: Integrin αIIb (CD4{01} plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol·Open. 2013·Apr·11; 2(5):525‑32. <·PMID:·23789102·>
• Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M: A vasculo‑protective circuit centered on lipoxin A4 and aspirin‑triggered 15‑epi‑lipoxin A4 operative in murine microcirculation. Blood. 2013·Jul·25; 122(4):608‑17. <·PMID:·23733341·>
• Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX: Stress‑induced hematopoietic failure in the absence of immediate early response gene X‑1. Haematologica. 2013·Sep·20; <·PMID:·23812939·>
• Sullivan BP, Wang R, Tawfik O, Luyendyk JP: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol·Sci. 2010·May; 115(1):286‑94. <·PMID:·20133375·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN