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CyFlow CD82 APC

品番 BJ045548
抗体名 Anti-Hu CD82 APC,C33
包装単位 100 tests
濃度 -
容量 1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG2a APC (AE606921)
反応性|交差吸着 Human レーザー Red
抗原 CD82, R2l 4F9, C33 最大蛍光波長 660 nm
クローン C33 最大励起波長 650 nm
ホスト Mouse 標識/Format APC
アイソタイプ IgG2a 研究分野 Immunophenotyping
クローナリティ monoclonal 用途

Flow cytometry

Anti-Hu CD82 APC,C33

特異性

The mouse monoclonal antibody C33 recognizes CD82 antigen, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

抗原情報

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumor-suppressive roles of CD82 have been demonstrated.

利用方法

The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ: Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B‑lymphocytes. J·Biol·Chem. 1998·Aug·7; 273(32):20121‑7. <·PMID:·9685355·>
• Fukudome K, Furuse M, Imai T, Nishimura M, Takagi S, Hinuma Y, Yoshie O: Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T‑cell leukemia virus type 1 (HTLV‑1)‑induced syncytium formation: altered glycosylation of C33 antigen in HTLV‑1‑positive T cells. J·Virol. 1992·Mar; 66(3):1394‑401. <·PMID:·1738199·>
• Imai T, Kakizaki M, Nishimura M, Yoshie O: Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82. J·Immunol. 1995·Aug·1; 155(3):1229‑39. <·PMID:·7636191·>
• Imai T, Yoshie O: C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells. J·Immunol. 1993·Dec·1; 151(11):6470‑81. <·PMID:·8245480·>
• Ueda T, Ichikawa T, Tamaru J, Mikata A, Akakura K, Akimoto S, Imai T, Yoshie O, Shiraishi T, Yatani R, Ito H, Shimazaki J: Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer. Am·J·Pathol. 1996·Nov; 149(5):1435‑40. <·PMID:·8909232·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD82 APC (C33) BJ045548 TDS (US)