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CyFlow DDIT4L PE

品番 AZ666112
抗体名 Anti-Hu DDIT4L PE,DDIT-03
包装単位 0.1 mg
濃度 0.1 mg/ml
容量 1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 PE (BV655324)
反応性|交差吸着 Human レーザー Blue, Green, Yellow
抗原 DDIT4L, DNA damage inducible transcript 4 like 最大蛍光波長 576 nm
クローン DDIT-03 最大励起波長 496 nm, 565 nm
ホスト Mouse 標識/Format PE
アイソタイプ IgG1 研究分野 Apoptosis
クローナリティ monoclonal 用途

Flow cytometry

Anti-Hu DDIT4L PE,DDIT-03

特異性

The mouse monoclonal antibody DDIT-03 recognizes DDIT4L antigen, which belongs to stress-induced proteins involved in mediation of cell death.

抗原情報

DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.

利用方法

The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Corradetti MN, Inoki K, Guan KL: The stress‑inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J·Biol·Chem. 2005·Mar·18; 280(11):9769‑72. <·PMID:·15632201·>
• Cuaz-Pérolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Negre-Salvayre A, Fruchart JC, Rouis M: REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death. Arterioscler·Thromb·Vasc·Biol. 2004·Oct; 24(10):1830‑5. <·PMID:·15308555·>
• Imen JS, Billiet L, Cuaz-Pérolin C, Michaud N, Rouis M: The regulated in development and DNA damage response 2 (REDD2) gene mediates human monocyte cell death through a reduction in thioredoxin‑1 expression. Free·Radic·Biol·Med. 2009·May·15; 46(10):1404‑10. <·PMID:·19268525·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ DDIT4L PE (DDIT-03) AZ666112 TDS (US)