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CyFlow CD271 Purified

品番 AV732768
抗体名 Anti-Hu CD271 PURI,NGFR5
包装単位 0.1 mg
濃度 1 mg/ml
容量 0.1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 Purified (BJ561896)
Mouse IgG1 Purified (AS224818)
反応性|交差吸着 Human | Non-Human Primates | Cat | Ferret | Rabbit レーザー
抗原 CD271, LNGFR, p75NTR 最大蛍光波長 -
クローン NGFR5 最大励起波長 -
ホスト Mouse 標識/Format Purified
アイソタイプ IgG1 研究分野 Immunophenotyping | Neurobiology
クローナリティ monoclonal 用途

Flow cytometry
Immunoprecipitation
Western blot
Immunohistochmistry (paraffin-embedded sections)
Immunocytochemistry

Anti-Hu CD271 PURI,NGFR5

特異性

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes CD271 antigen, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.

抗原情報

CD271 (NGFR, p75NGFR, p75NTR) is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Alpers CE, Hudkins KL, Ferguson M, Johnson RJ, Schatteman GC, Bothwell M: Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys. Lab·Invest. 1993·Dec; 69(6):703‑13. <·PMID:·7903404·>
• Marano N, Dietzschold B, Earley JJ Jr, Schatteman G, Thompson S, Grob P, Ross AH, Bothwell M, Atkinson BF, Koprowski H: Purification and amino terminal sequencing of human melanoma nerve growth factor receptor. J·Neurochem. 1987·Jan; 48(1):225‑32. <·PMID:·3025363·>
• Schatteman GC, Gibbs L, Lanahan AA, Claude P, Bothwell M: Expression of NGF receptor in the developing and adult primate central nervous system. J·Neurosci. 1988·Mar; 8(3):860‑73. <·PMID:·2831315·>
• Thompson SJ, Schatteman GC, Gown AM, Bothwell M: A monoclonal antibody against nerve growth factor receptor: Immunohistochemical analysis of normal and neoplastic human tissue. Am·J·Clin·Pathol. 1989·Oct; 92(4):415‑23. <·PMID:·2552791·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD271 Purified (NGFR5) AV732768 TDS (US)