CyFlow CD82 Biotin
| 品番 | AV116998 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu CD82 BIOTIN,C33 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 1 mg/ml | ||
| 容量 | 0.1 ml | ||
| 関連製品 (アイソタイプコントロール) |
Mouse IgG2a Biotin (BH298720) |
||
| 反応性|交差吸着 | Human | レーザー | |
| 抗原 | CD82, R2l 4F9, C33 | 最大蛍光波長 | - |
| クローン | C33 | 最大励起波長 | - |
| ホスト | Mouse | 標識/Format | Biotin |
| アイソタイプ | IgG2a | 研究分野 | Immunophenotyping |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu CD82 BIOTIN,C33
特異性
The mouse monoclonal antibody C33 recognizes CD82 antigen, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
抗原情報
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumor-suppressive roles of CD82 have been demonstrated.
利用方法
The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ: Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B‑lymphocytes. J·Biol·Chem. 1998·Aug·7; 273(32):20121‑7. <·PMID:·9685355·>
• Fukudome K, Furuse M, Imai T, Nishimura M, Takagi S, Hinuma Y, Yoshie O: Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T‑cell leukemia virus type 1 (HTLV‑1)‑induced syncytium formation: altered glycosylation of C33 antigen in HTLV‑1‑positive T cells. J·Virol. 1992·Mar; 66(3):1394‑401. <·PMID:·1738199·>
• Imai T, Kakizaki M, Nishimura M, Yoshie O: Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82. J·Immunol. 1995·Aug·1; 155(3):1229‑39. <·PMID:·7636191·>
• Imai T, Yoshie O: C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells. J·Immunol. 1993·Dec·1; 151(11):6470‑81. <·PMID:·8245480·>
• Ueda T, Ichikawa T, Tamaru J, Mikata A, Akakura K, Akimoto S, Imai T, Yoshie O, Shiraishi T, Yatani R, Ito H, Shimazaki J: Expression of the KAI1 protein in benign prostatic hyperplasia and prostate cancer. Am·J·Pathol. 1996·Nov; 149(5):1435‑40. <·PMID:·8909232·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN