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CyFlow CD326 PerCP-Cy5.5

品番 AS190365
抗体名 Anti-Hu CD326 PERCP-CY5.5,VU-1D9
包装単位 100 tests
濃度 -
容量 0.4 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 PerCP-Cy5.5 (CZ886982)
反応性|交差吸着 Human レーザー Blue, Green
抗原 CD326, EpCAM, Ep-CAM 最大蛍光波長 695 nm
クローン VU-1D9 最大励起波長 482 nm
ホスト Mouse 標識/Format PerCP-Cy5.5
アイソタイプ IgG1 研究分野 Immunophenotyping
クローナリティ monoclonal 用途

Flow cytometry

Anti-Hu CD326 PERCP-CY5.5,VU-1D9

特異性

The mouse monoclonal antibody VU-1D9 recognizes an epitope within EGF-like domain I of CD326 (EpCAM) antigen, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.

抗原情報

CD326 (EpCAM, ESA, EGP40, EGP-2, KSA1/4, CO17-1A, GA733-2, MOC31, Ber-EP4) is a 40 kDa transmembrane glycoprotein serving as adhesion molecule in the basolateral membranes in a variety of epithelial cells. CD326 mediates calcium-independent homotypic cell-cell adhesions. CD326 over-expression has been detected in many epithelial tumors and is often associated with bad prognosis. It has been used for diagnostics of (pre-) malignancies at early stages.

利用方法

The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Brunner A, Prelog M, Verdorfer I, Tzankov A, Mikuz G, Ensinger C: EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J·Clin·Pathol. 2008·Mar; 61(3):307‑10. <·PMID:·17586680·>
• Li G, Passebosc-Faure K, Lambert C, Gentil-Perret A, Blanc F, Oosterwijk E, Mosnier JF, Genin C, Tostain J: Flow cytometric analysis of antigen expression in malignant and normal renal cells. Anticancer·Res. 2000·Jul-Aug; 20(4):2773‑8. <·PMID:·10953356·>
• Ogura E, Senzaki H, Yoshizawa K, Hioki K, Tsubura A: Immunohistochemical localization of epithelial glycoprotein EGP‑2and carcinoembryonic antigen in normal colonic mucosa and colorectal tumors. Anticancer·Res. 1998·Sep-Oct; 18(5B):3669‑75. <·PMID:·9854475·>
• Tsubura A, Senzaki H, Sasaki M, Hilgers J, Morii S: Immunohistochemical demonstration of breast‑derived and/or carcinoma‑associated glycoproteins in normal skin appendages and their tumors. J·Cutan·Pathol. 1992·Feb; 19(1):73‑9. <·PMID:·1556271·>
• Winter MJ, Nagtegaal ID, van Krieken JH, Litvinov SV: The epithelial cell adhesion molecule (Ep‑CAM) as a morphoregulatory molecule is a tool in surgical pathology. Am·J·Pathol. 2003·Dec; 163(6):2139‑48. <·PMID:·14633587·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD326 PerCP-Cy5.5 (VU-1D9) AS190365 TDS (US)