特異性

The mouse monoclonal antibody 1-155-2 recognizes λ light chains (22.5 kDa) of human immunoglobulin.

抗原情報

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (κ and λ; both having a molecular weight of 22.5kDa). κ and λ consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of κ to λ is 70:30.

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Bahler DW, Pindzola JA, Swerdlow SH: Splenic marginal zone lymphomas appear to originate from different B cell types. Am·J·Pathol. 2002·Jul; 161(1):81‑8. <·PMID:·12107092·>
• Kubagawa H, Gathings WE, Levitt D, Kearney JF, Cooper MD: Immunoglobulin isotype expression of normal pre‑B cells as determined by immunofluorescence. J·Clin·Immunol. 1982·Oct; 2(4):264‑9. <·PMID:·6815220·>
• Tierens AM, Holte H, Warsame A, Ikonomou IM, Wang J, Chan WC, Delabie J: Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B‑cell lymphoma of activated B‑cell type but not of germinal center B‑cell type. Haematologica. 2010·Aug; 95(8):1334‑41. <·PMID:·20145271·>