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CyFlow CD253 Low Endotoxin

品番 AM151429
抗体名 Anti-Hu CD253 LOW END,2E5
包装単位 0.1 mg
濃度 1 mg/ml
容量 0.1 ml
関連製品
(アイソタイプコントロール)
Mouse IgG1 Low Endotoxin (AK478344)
反応性|交差吸着 Human レーザー
抗原 CD253, TRAIL, Apo2L 最大蛍光波長 -
クローン 2E5 最大励起波長 -
ホスト Mouse 標識/Format Low Endotoxin
アイソタイプ IgG1 研究分野 Immunophenotyping | Apoptosis
クローナリティ monoclonal 用途

Flow cytometry
Functional assays

Anti-Hu CD253 LOW END,2E5

特異性

The mouse monoclonal antibody 2E5 recognizes CD253 (TRAIL) antigen, a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.

抗原情報

CD253 (TRAIL; TNF-Related Apoptosis Inducing Ligand or Apo2) is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC: Synthetic triterpenoids cooperate with tumor necrosis factor‑related apoptosis‑inducing ligand to induce apoptosis of breast cancer cells. Cancer·Res. 2005·Jun·1; 65(11):4799‑808. <·PMID:·15930300·>
• Plasilova M, Zivny J, Jelinek J, Neuwirtova R, Cermak J, Necas E, Andera L, Stopka T: TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors. Leukemia. 2002·Jan; 16(1):67‑73. <·PMID:·11840265·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD253 Low Endotoxin (2E5) AM151429 TDS (US)