フローサイトメーター

世界のリサーチ分野のお客さまへ先端の検査装置のご案内です。

  • 神戸:078-992-6272
  • 東京:03-5434-8556

【受付時間09:00~17:35※土日休日を除く/その他休日はサイト上で告知

お問い合わせ

sysmex

フローサイトメーターsysmex

CyFlow CD108 Purified

品番 AD536081
抗体名 Anti-Hu CD108 PURI,MEM-150
包装単位 0.1 mg
濃度 1 mg/ml
容量 0.1 ml
関連製品
(アイソタイプコントロール)
Mouse IgM Purified (AP063643)
反応性|交差吸着 Human レーザー
抗原 CD108, SEMA7A, GPI-gp80, JMH 最大蛍光波長 -
クローン MEM-150 最大励起波長 -
ホスト Mouse 標識/Format Purified
アイソタイプ IgM 研究分野 Immunophenotyping | Blood group antigens
クローナリティ monoclonal 用途

Flow cytometry
Immunoprecipitation
Western blot

Anti-Hu CD108 PURI,MEM-150

特異性

The mouse monoclonal antibody MEM-150 recognizes CD108 antigen, a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.

抗原情報

CD108 (SEMA7A; Semaphorin 7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and β1 integrins.

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Angelisová P, Drbal K, Cerny J, Hilgert I, Horejsi V: Characterization of the human leukocyte GPI‑anchored glycoprotein CDw108 and its relation to other similar molecules. Immunobiology. 1999·Jun; 200(2):234‑45. <·PMID:·10416131·>
• Delorme G, Saltel F, Bonnelye E, Jurdic P, Machuca-Gayet I: Expression and function of semaphorin 7A in bone cells. Biol·Cell. 2005·Jul; 97(7):589‑97. <·PMID:·15859945·>
• Doussis IA, Gatter KC, Mason DY: CD68 reactivity of non‑macrophage derived tumours in cytological specimens. J·Clin·Pathol. 1993·Apr; 46(4):334‑6. <·PMID:·7684403·>
• Mudad R, Rao N, Angelisova P, Horejsi V, Telen MJ: Evidence that CDw108 membrane protein bears the JMH blood group antigen. Transfusion. 1995·Jul; 35(7):566‑70. <·PMID:·7631388·>
• Pasterkamp RJ, Kolk SM, Hellemons AJ, Kolodkin AL: Expression patterns of semaphorin7A and plexinC1 during rat neural development suggest roles in axon guidance and neuronal migration. BMC·Dev·Biol. 2007·Aug·29; 7:98. <·PMID:·17727705·>
• Pasterkamp RJ, Peschon JJ, Spriggs MK, Kolodkin AL: Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature. 2003·Jul·24; 424(6947):398‑405. <·PMID:·12879062·>
• Suzuki K, Okuno T, Yamamoto M, Pasterkamp RJ, Takegahara N, Takamatsu H, Kitao T, Takagi J, Rennert PD, Kolodkin AL, Kumanogoh A, Kikutani H: Semaphorin 7A initiates T‑cell‑mediated inflammatory responses through alpha1beta1 integrin. Nature. 2007·Apr·5; 446(7136):680‑4. <·PMID:·17377534·>
• Kishimoto T, Goyert S, Kikutani H, Mason D, Miyasaka M, Moretta L, Ohno T, Okumura K, Shaw S, Springer TA, Sugamura K, Sugawara H, von dem Borne AEGK, Zola H (Eds): Leucocyte Typing VI. Garland·Publishing·Inc,·New·York. 1997; 1‑1342. <·NLM·ID:·9712219·>

Available Safety Data Sheets

CyFlow™ monoclonal antibodies SDS CA EN

Available Technical Data Sheets

CyFlow™ CD108 Purified (MEM-150) AD536081 TDS (US)