CyFlow Lysozyme FITC
| 品番 | AC017849 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu Lysozyme FITC,LZ598-10G9 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 1 mg/ml | ||
| 容量 | 0.1 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Human | レーザー | Blue |
| 抗原 | Lysozyme | 最大蛍光波長 | 518 nm |
| クローン | LZ598-10G9 | 最大励起波長 | 490 to 495 nm |
| ホスト | Mouse | 標識/Format | FITC |
| アイソタイプ | IgG1 | 研究分野 | Immunophenotyping | Blood group antigens |
| クローナリティ | monoclonal | 用途 | Flow cytometry |
Anti-Hu Lysozyme FITC,LZ598-10G9
特異性
The mouse monoclonal antibody LZ598-10G9 recognizes lysozyme, a 17 kDa antibacterial enzyme, which is being used as a marker for the lineage diagnosis of acute leukemias.
抗原情報
Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils). It damages bacterial cell walls by hydrolysis of 1,4-β-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium.
利用方法
The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Strobl H, Knapp W: Myeloid cell‑associated lysosomal proteins as flow cytometry markers for leukocyte lineage classification. J·Biol·Regul·Homeost·Agents. 2004·Jul-Dec; 18(3‑4):335‑9. <·PMID:·15786701·>
Available Safety Data Sheets
CyFlow™ monoclonal antibodies SDS CA EN